How does shakespeare present macbeth as a troubled man in act 1 scene 3

Read the excerpt from “strychnine in the soup,” in which mr. mulliner explains the ending of a mystery novel to a bar patron who is anxious to know the conclusion of the story. “the plumber forgot his snake and had to go back for it,” explained mr. mulliner. ‘‘i trust that this revelation will prove sedative.” “i feel a new man,” said the draught stout. “i’d have lain awake worrying about that murder all night.” explain how a student who did not know the meaning of sedative could infer its definition?