Read the passage from hamlet, act i, scene iii. hamlet: my fate cries out, and makes each petty artery in this body as hardy as the nemean lion’s nerve. [ghost beckons.] still am i call’d. unhand me, gentlemen, [breaking from them.] by heaven! i’ll make a ghost of him that lets me: i say, away! go on, i’ll follow thee. [exeunt ghost and hamlet.] which phrase from the passage most create a tone of desperation

I would say that the phrase from the passage that most helps create a tone of desperation is: "By heaven! I’ll make a ghost of him that lets me"

Explanation:

This line shows the character's despair, show how he feels hopeless. He is asking, almost begging for his fate ("By heaven!"), he even makes a promise to whomever would help him to change his fate (I’ll make a ghost of him that lets me). This phrase shows desperation, he screams begging for help.