Which two words from the passage contribute to create a mood of desperation?

In the story, juvencio states that he had to kill don lupe. what does this line reveal about how he views his deed? (tell them not to kill me)

In what way is victor frankenstein, instead of his creation, most clearly monstrous? a.he disconnects from his family and friends. b.he wishes that he could control the world with his monster. c.he believes that he can achieve success in the scientific world. d.he becomes angry at the monster, even though he created it.

When mrs. jameson says "it (the desert) won't leave you cold," what does she mean?