What should be taken into consideration when determining which critical information should be protected?

What data would cause harm if exposed to adversaries, the type of threats, risks, and vulnerabilities.

Explanation:

Operations security (OPSEC) is a process or method organizations use to analyze or assess data to be protected to prevent data leaks that would cause harm to their activities.

It is always important to determine critical information that should be confidential to the organization as well as potential risks, threats and vulnerabilities in the company.