Which of the following does not describe local alignment algorithm?
a) score can be negative
b) negative score is set to 0
c) first row and first column are set to 0 in initialization step
d) in traceback step, beginning is with the highest score, it ends when 0 is encountered

The answer is "Option a".

Explanation:

A score can be detrimental. When an element has a score below zero, it means, that the sequences up to this point have no correlations, that are set to zero and its effects the previous alignment is excluded. Thus, alignment can be further found in every position later in the calculation. and other options are incorrect that can be described as follows:

what is your question exactly? when you let me know i will gladly you. : )

plot immersion i am not fully sure with it though