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How would individuals with decreased levels of the pentose phosphate enzyme glucose-6-phosphate dehydrogenase respond to oxidative stress?

1. they would rapidly neutralize cellular levels of h2o2 and other reactive oxygen species.
2. they would compensate with higher than normal levels of pentose phosphate pathway activity.
3. they would not have the ability to regenerate reduced glutathione as rapidly.
4. none of these answers are correct.
5. higher than normal levels of nadph would accumulate.

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