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Chemistry, 17.09.2021 14:00 nerdywolf2003

Research a medication not discussed in class that utilizes enzyme inhibition for its mechanism of action. You should briefly comment on how the medicine’s regulation of the target enzyme has a therapeutic effect. Describe the type of inhibition this medication induces for its effect, not by simply listing the category, but explaining the interaction between the medication and its target enzyme. How does the presence of this medication influence the Km and Vmax of the enzyme (i. e., explain, in your own words, how the shifts observed for this kind of inhibitor make sense on the Lineweaver-Burke plot)? Based on the chemical configuration/functional groups of the chosen medicine, as well as the enzyme’s usual substrate or allosteric regulators, what can you infer about the amino acids at either the active or allosteric site of the target enzyme? This point does not have to be supported by research evidence but draw your own logical conclusions about these complementary interactions; you can be creative but be logical.

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