The predominant consequence to an individual who is genetically deficient in liver fructose 1,6-bisphosphatase would be A. Inability to metabolize fructose.

B. a lowered yield of ATP production per mole of glucose metabolized.

C. a failure to split fructose bisphosphate into triose phosphates.

D. a failure to resynthesize glucose from lactic acid.​

The predominant consequence to an individual who is genetically deficient in liver fructose 1,6-bisphosphatase would be failure to resynthesize glucose from lactic acid.​

WHAT IS FRUCTOSE 1,6-BISPHOSPHATASE:

fructose 1,6-bisphosphatase is an important enzyme produced in the liver to catalyze the conversion of fructose-1,6-bisphosphate to fructose-6-phosphate during gluconeogenesis. Gluconeogenesis is the process whereby glucose sugar is produced from noncarbohydrate substances such as lactate, pyruvate etc. Gluconeogenesis is the opposite of glycolysis (breakdown of glucose).

CONSEQUENCES OF DEFICIENCY OF FRUCTOSE 1,6-BISPHOSPHATASE:

Since, gluconeogenesis results in the synthesis of glucose from substances like lactic acid, a deficiency in liver fructose 1,6-bisphosphatase enzyme will mean that GLUCOSE WILL NOT BE ABLE TO BE SYNTHESIZED.

Therefore, the predominant consequence to an individual who is genetically deficient in liver fructose 1,6-bisphosphatase would be failure to resynthesize glucose from lactic acid.​

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