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For a reacion that take place with or withoug catalysis by an enzyme what would be the effect of the enzyme on the standard free energy change of the reaction?

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For a reacion that take place with or withoug catalysis by an enzyme what would be the effect of the enzyme on the standard free energy change of the reaction? ​

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For a reacion that take place with or withoug catalysis by an enzyme what would be the effect of the enzyme on the standard free energy change of the reaction?