Why would it be more difficult to inject the nucleus of uranium with a proton?

Because there are already 92 protons in the

uranium nucleus, combining their repulsive power to reject the one new one. However, if the energy of the incoming proton is sufficiently great, then at extremely close distance, the uranium nucleus will attract the proton and draw it into the nucleus. This is called the strong force.

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Explanation:

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< > according to newton's third law of motion, forces always act in equal but opposite pairs. another way of saying this is for every action, there is an equal but opposite reaction.< >