Fructose‑2,6‑bisphosphate is a regulator of both glycolysis and gluconeogenesis for the phosphofructokinase reaction of glycolysis and the fructose‑1,6‑bisphosphatase reaction of gluconeogenesis. In turn, the concentration of fructose‑2,6‑bisphosphate is regulated by many hormones, second messengers, and enzymes.

Activate glycolysis/Inhibit gluconeogenesis: Increased levels of fructose-2,6-bisphosphate, activation of PFK-2

Activate gluconeogenesis/Inhibit glycolysis: Increased levels of glucagon, Increased levels of cAMP, Activation of fructose-2,6-bisphosphatase (FBPase-2)

Note: The question is incomplete. The complete question is given below and in the attachment.

Fructose‑2,6‑bisphosphate is a regulator of both glycolysis and gluconeogenesis for the phosphofructokinase reaction of glycolysis and the fructose‑1,6‑bisphosphatase reaction of gluconeogenesis. In turn, the concentration of fructose‑2,6‑bisphosphate is regulated by many hormones, second messengers, and enzymes. How do the following affect glycolysis and gluconeogenesis?

Explanation:

Fructose-2,6-bisphosphate is an allosteric effector for the enzymes phosphofructokinase-1 (PFK-1) and fructose-1,6-bisphosphatase (FBPase-1). It increases the affinity of PFK-1 for fructose-6-phosphate thereby activating glycolysis. However, it reduces the affinity of FBPase-1 for its substrate, fructose-1,6-bisphosphate thereby inhibiting gluconeogenesis.

Activation of phosphofructokinase-2 activates glycolysis and inhibits gluconeogenesis by catalyzing the phosphorylation of fructose-6-phosphate to form fructose-2,6-bisphosphate.

Increased levels of glucagon stimulates the synthesis of cAMpP which activates cAMP-dependent ptrotein kinase which phosphorylates the bifunctional enzyme PFK-2/FBPase-2. The phosphorylation of this enzyme inhibits its PFK-2 activity and activates its FBPase-2 activity. This results in the activation of gluconeogenesis and inhibition of glycolysis.

Fructose-2,6-bisphosphatase breaks down fructose-2,6-bisphosphate to fructose-6-phospshate and a phosphoryl group. This results in the activation of gluconeogenesis and the inhibition of glycolysis.

- calcium has greater affinity to bond with electron receptors than hydrogen does and hence, it has the ability to replace hydrogen in most of its compounds.

- lithium has 2 valence electrons in the product because it can make only 1 bond with hydrogen. beryllium has 4 valence electrons in the product because it can only make 2 bonds. it has fewer electrons than neon and can react with electron donors. each hydrogen has 2 valence electrons, the same as helium.

- the covalent bond formed between carbon and hydrogen is polar because carbon is more electronegative than hydrogen and it attracts the bonded electron pair closer to itself, thus giving hydrogen a partial positive charge.

- a hydrogen bond is a relatively weak bond that hydrogen atoms make with the electronegative atoms nitrogen, oxygen or fluorine.

so the best choice is a.) 2 calcium (ca) atoms