Compared to an enzyme with a Km of 10-6 mM, an enzyme having a Km of 10-8 mM

A. would have 100 times more product formed per min
B. would be described as having binding more tightly to the substrate
C. would be described as having a significantly lower affinity for the substrate
D. would have a Vmax 100 times larger
E. would have identical values for Vmax

Explanation:

Compared to an enzyme with a Km of 10-6 mM, an enzyme having a Km of 10-8 mM

The correct answer is option B - would be described as having binding more tightly to the substrate

Reason:

Km is the measure of substrate affinity. It is inversely proportional. Higher the Km, lower is the binding affinity of the enzyme and lower the Km, higher binding affinity of the enzyme to the substrate.

Therfore, Km of 10⁻⁸ will have higher substrate binding affinity than the 10⁻⁶ enzyme.