reactions are used to detect antibodies for relatively large pathogens

The question is incomplete, no worries I got you.

Here is the complete question;

reactions are used to detect antibodies for relatively large pathogens, such as bacteria. For these tests, the antigen is mixed with the test sample at various dilutions. Reaction mixes are then monitored for the formation of visible aggregates.

Explanation:

AGGLUTINATION is the reaction used.

Agglutination is the reaction in which there is the clumping of particles. A agglutination reaction is the visible clumping of the bacterial cells as an antigen reacts with its corresponding antibody. This type is often used as an initial confirmation of specific pathogens. Agglutination tests is is used to detect antibody or antigen and it involves the  agglutination of bacteria, red cells, or antigen- or antibody-coated latex particles. It is therefor used for large pathogens like bacteria. In this reaction, antigens are introduced into various dilutions of antibodies in test tubes or surfaces of glass slides, visible clumping is observed which depends on the size of the antibodies, amount and acidity of the antibody molecule, time of incubation and as well as the environment of the reaction which includes optimum pH, protein concentration among others.  

the tides are influenced by both the moon and the sun, it's easy to see that when the sun lines up with the moon and the earth, as during a new moon or full moon, the tidal effect is increased. these are known as spring tides, named not for the season, but for the fact that the water "springs" higher than normal. on the other hand, if the sun and the moon are 90 degrees apart in relation to an observer on earth as during the first quarter moon or third quarter moon, then high tides are not as high as they normally would be. this is because despite its greater distance, the sun's mass allows it to exert enough gravitational force on the oceans that it can negate some of the effects of the moon's pull. this phenomenon of lower high tides is called a neap tide. if you need more information on this topic visit moonconnection.com.