A mixture of nonpolar compounds is separated by hplc using an octyl (–(ch2)7ch3) stationary phase covalently bonded to the silica support. how would the retention times of the compounds change if the solvent composition was changed from 55 vol% acetone and 45 vol% water to 85 vol% acetone and 15 vol% water?

Amines are good nucleophiles, even though they are neutral molecules. how would the rate of an sn2 reaction between an amine and an alkyl halide be affected if the polarity of the solvent is increased? amines are good nucleophiles, even though they are neutral molecules. how would the rate of an reaction between an amine and an alkyl halide be affected if the polarity of the solvent is increased? because both reactants in the rate-limiting step are neutral, the reaction will be faster if the polarity of the solvent is increased. because both reactants in the rate-limiting step are neutral, the reaction will be slower if the polarity of the solvent is increased. because both reactants in the rate-limiting step are neutral, the reaction will occur at the same rate if the polarity of the solvent is increased. request answer