Lavoisier made a list of thirty-three elements. His list of elements challenged the age-old idea that
elements are made of atoms.
there are only four elements.
elements cannot be identified
elements do not exist in the free state.

He challenged the idea of Phlogiston; that it was in fact not something trapped in flammable things, it was a gas (Oxygen) that allowed some things to burn.

Explanation:

He took a Mercury Oxide, in a glass vessel; he heated it with a magnifying glass to yield Hg and O2.

some sources quote the lethal dose, for an average 170lbs opiate-naive individual is between 75 and 375 mg

the enthalpy of formation of water is given as -285.8kj/mol, which states that the enthalpy of formation is negative.

negative enthalpy of formation indicates that the heat is released during the reaction process. the heat is released from reaction to the surroundings the enthalpy is expressed with a negative sign with the energy given out in the reaction process.

the formation of water takes place by giving out heat which is -285.8 kj/mol.