The transcription factor ap-1 is a heterodimer consisting of c-jun and c-fos. c-jun and c-fos are soluble proteins that can be localized to either the cytosol or nucleus of a cell. c-jun and c-fos dimerize through a leucine zipper motif. in a leucine zipper motif, every 7 amino acid residues, or 2 full turns of an alpha helix, are leucine resides. leucine and other amino acids on one face of the helix come together to form an opposite alpha helix that has a similar arrangement of leucine and other amino acids. which solvent would be least favorable for c-fos/c-jun dimerization?

Hexane

Explanation:

Generally, leucine is hydrophobic in nature and it has a carbon-hydrogen side chain. Therefore, it is not advisable to use an hydrophobic solvent because the leucine zipper would interact with both the opposite alpha helix and the solvent. This will ultimately hinder the dimer creation. Thus, the best solvent which is the least polar in the list is hexane.  

nacl or sodium chloride is an ionic compound. this is because an ionic compound pertains to a compound that consists of positively and negatively charged ions. in this case, na (sodium) has a tendency to lose one electron when it reacts with with other atoms, so the resulting sodium ion contains 11 protons and 10 electrons, thus making it positively charged (na+), when chlorine reacts, it usually gains one electron to form an ion called chloride, thus making it negatively charged ( since the ions are oppositely charged, they attract.