Mutations in genes encoding cell signaling proteins contribute to many cancers. for example, a chromosomal translocation fuses the bcr gene to the abl gene, leading to a constitutively active bcr–abl kinase and chronic myeloid leukemia (cml). cml is successfully treated with the drug imatinib (trade name gleevec), which mimics an abl kinase substrate and thus inhibits kinase activity. what normal cell molecule, and kinase substrate, does gleevec mimic?

Imatinib is a small molecule kinase inhibitor. The BCR-ABL kinase can phosphorylate a series of downstream substrates, leading to proliferation of mature granulocytes. Bcr-Abl kinase substrate is the tyrosine. The Protein Tyrosine Kinase activity is an important requirement for malignant transformation, and that it cannot be complemented by any downstream effector, though not all interactions of BCR-ABL with other proteins are phosphotyrosine dependent.

explanation:

let the different atoms be x and y. each with four protons and same mass will be represented as follows.

mass number is number of protons + number of neutrons.

            and  

since, it is given that one has a negative charge while the other is neutral. therefore, there will be increase in number of protons and the atom will be represented as follows.

according to periodic table, mass number of beryllium is 9 and it has atomic number 4 so, the atoms will be and .  

the protons and neutrons will be located inside the nucleus whereas the electrons will be revolving around the nucleus.  

i think the answer is terrae but not 100 percent sure. ▓▬▬ §