What is the benefit of substrate channeling? the pdh active site forms in the hydrophobic core of the complex instead of a surface‑exposed region. reaction intermediates move to sequential active sites faster than the diffusion constant. every intermediate or product made by the pdh complex enters the citric acid cycle as a substrate. the pdh complex sequesters excess substrate to use at later time. intermediates of a multistep reaction sequence do not dissociate from the enzyme complex.

answer is: naturally occurring solid, inorganic compound or element is mineral.

minerals usually have crystalline form, that means than crystal constituents (atoms, molecules or ions) are arranged in a highly ordered microscopic structure, forming a crystal lattice that extends in all directions.

for example magnetite is a mineral of iron oxide (fe₂o₃).

calcite is a carbonate mineral and the most stable polymorph of calcium carbonate (caco₃).

dolomite is an   carbonate mineral composed of calcium magnesium carbonate (camg(co₃)₂).

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