Drag the labels to complete each sentence that discusses the development of viral-induced cancer. 1. During the normal functioning of the eukaryotic cell cycle proteins are essential to ensure errors are not perpetuated throughout the cell line.
2. Two important genes that code for these proteins are , that initiate cell division at the appropriate time, genes, which control the cycle checkpoints.
3. Viruses can disrupt the expression of these genes; mutation in a proto-oncogene results in the initiation of cell division in the of the appropriate signal.
4. Mutation in a tumor-suppressor gene renders the protein allowing uncontrolled division of the cell.
5. Cells that have lost the ability to undergo as is the case when the tumor-suppressor gene is mutated, will develop into a tumor.
a. apoptosis
b. inactive
c. p53
d. proto-oncogenes
e. presence
f. absence
g. regulatory
h. Myc
i. tumor-suppressor
j. active