Under what condition would a mutation have the most impact on allele frequency

I think this happens when there is no gene flow or when the population is small. Small population, germ line mutation, beneficial mutation that gets into many progeny and is of  high chance of luck. Genetic drift involves a process in which allele frequencies within a population change by chance only, as a result of sampling error from generation to generation. Genetic drift occurs mostly in small population since the infrequently occurring alleles face a greater chance of being lost.

I'm sorry to hear that. i will try to answer your other questions if it is within my ability. : )answers: my favourite colour is black.my favourite food is pasta.my favourite school subject is english, but i do also like lunch time.my least favourite subject is history as well as geography. i have currently garnered a quite equal hatred for both of the subjects.what about you? well, you for the points. : )