Which action shows a creative approach to the process of scientific inquiry?

developing a technique for observing an object that has yet to be observed

Thus, to achieve the creative approach above the researchers must utilize and apply the scientific method in gathering, interpreting and analyzing empirical evidence. 

Empirical evidence, data or knowledge is an obtained set of facts or figures or existing and presenting data that was yielded during the process of experimentation or scientific discovery. These empirical data or evidence is further studied and investigated by the scientist in a formal scientific approach which follows the steps of observation, making a hypothesis, gathering data, interpreting data and evaluating the data. These steps of the scientific approach are vital in the course to explain and discuss the result and evidence obtained during the process. 

Ribonuclease activity is a type of nuclease that catalyzes the degradation of rna into small components.