Which enzymes serve as catalysts in metabolism?

In biochemical reactions, it is mostly triggered by enzymes. Enzymes are important components in the process that involves metabolism and digestive functions, further, most of these enzymes are proteins.Proteins are biological macromolecule and mostly composed of enzymes. Proteins play a role in the physical make-up of a cell or acts as a cytoskeleton –maintains cell shape and figure. These proteins plays different roles and works with nucleic acids and other macromolecules in the cells including cell cycle, cell adhesion, immune response and cell indicators.  

Telophase colchicine is a chemical obtained from plants that prevents the assembly of spindle fibers