The main difference between prokaryotic and eukaryotic cells is a. eukaryotic cells have a more complex cellular organization. b. eukaryotic cells have a smaller cell nucleus. c. prokaryotic cells are always much larger. d. prokaryotic cells do not have a plasma membrane.

Hey! The main difference between a prokaryotic cell and a eukaryotic cell from your options would have to be that eukaryotic cells have a more complex cellular organization. The reason for that is because there isn't much that makes up a prokaryotic cell, whereas the eukaryotic cell is made up of much more components, such as, the nucleus, lysosomes, endoplasmic reticulum and the mitochondria.