Fibroblast cells can migrate between tissues, whereas epithelial cells adhere strongly to each other and resist stretching. based on this description, you could surmise that would have more intermediate filaments than

enzyme active site and substrate specificity

enzymes bind with chemical reactants called substrates. there may be one or more substrates for each type of enzyme, depending on the particular chemical reaction. in some reactions, a single-reactant substrate is broken down into multiple products