Secretion of insulin from the pancreas is increased in response to

The pancreatic cells act as a self-contained system to secrete insulin in response to changes in ambient blood glucose concentration, in order to maintain glucose homeostasis. Glucose is freely taken up into the  cell via GLUT transporters, metabolized to produce ATP, which triggers a cascade of signals within the  cell necessary for glucose-induced insulin secretion. 

frogs. the lower the ph the higher the acid content. frogs have the highest tolerance in this scenario.

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