Abnormal levels of norepinephrine are linked to anxiety and depression. serotonin is linked to depression, if at a low level of serotonin.
Alterations in neurotransmitter synthesis are known to be associated with several neurological problems. The excess or scarcity of these neurotransmitters can cause serious problems to the mental health of individuals and therefore, drugs that alter the concentration of norepinephrine should be accompanied by a doctor. In relation to norepinephrine, its scarcity is associated with deep depression and its excess, anxiety and mania, which is the opposite of depression.
From this we can state that abnormal levels of norepinephrine are linked to anxiety and depression.