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An experimental drug has been added to a eukaryotic cell, and while the drug was designed to interfere with a membrane transport process, the investigators found that in cells treated with the drug the lysosomes quickly turned into inclusion bodies. None of the material directed to the lysosomes for removal was being digested in the lysosome, and remained intact inside the organelle. An analysis of lysosomal contents in drug-treated cells indicated that the full complement of lysosomal enzymes were present in the organelle.
Required:
Assuming that the drug is targeting just one protein, what proteins is most likely the target?
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An experimental drug has been added to a eukaryotic cell, and while the drug was designed to interfe...
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