4. Nebulin is an actin-binding protein that can be found in skeletal muscles. Nebulin is large in size and functions to stabilize actin and regulate muscle contractions. The gene that codes for nebulin, NEB, is on chromosome 2 in
humans. Mutations to the NEB gene can result in mutations in the amino acid sequence of the resulting nebulin
protein. If the mutation in the gene causes an amino acid deletion in the sequence of amino acids that make up
nebulin, how will this affect the structure of nebulin?
a. Only the primary structure of Nebulin will be affected; the secondary and tertiary structures will not be
affected.
b. Both the primary structure and secondary structure of nebulin will be affected, while the tertiary form will
not be affected.
c. The primary, secondary, and tertiary structures of nebulin will be affected.
d. An amino acid deletion would not affect the structure of nebulin.