How could a decline in the number of oocytes comrribute to change in hormones

enzyme active site and substrate specificity

enzymes bind with chemical reactants called substrates. there may be one or more substrates for each type of enzyme, depending on the particular chemical reaction. in some reactions, a single-reactant substrate is broken down into multiple products

the wetland preservation movement began in the u.s. in earnest with the clean water act (cwa) of 1972. although not specifically written to protect wetlands, the cwa is comprised of a series of regulations designed to prevent pollutants from contaminating u.s. waters.

the last one: artificial selection/genetic engineering

plant breeding is modifying the genetic composition of the plant - but this isn't cloning (which is specifically introducing a gene into a genome). but you are artificially selecting for the phenotype that you want.

the second one is literally genetic engineering - the gene would have been cloned first and then inserted or genetically engineered into the new plant cell (the cotton).