Which cellular change in an organism could be inherited by the next generation?

Changes in DNA result in mutations, which may be beneficial, neutral, or deleterious to the organism. If these changes occur to DNA in sperm or egg cells, they could be passed onto the next generation. Evolution consists of changes in the heritable traits of a population of organisms as successive generations replace one another.

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i would say the prokaryotic cells the prokaryotic cells are less complex, are usually found only in unicellular organisms and have more limited capabilities than eukaryotic cells.