Biology, 13.08.2021 02:10 abby894927
Several mutational changes to proteins involved in apoptosis are listed below. For each, indicate whether you expect it to have a dominant-negative phenotype. In other words, do you expect it to cause a defect in apoptosis even in cells that also contain the normal protein?
A. Deletion of death domain of Fas death receptor.
B. Mutational change to Fas ligand that prevents its oligomerization.
C. Deletion of the death effector domain of FADD.
D. Deletion of the death effector domain of procaspase-8.
E. Deletion of the CARD domain of Apaf-1.
F. Mutation of the catalytic cysteine of caspase-8 to serine.
G. Mutational change to Bax that prevents its oligomerization with itself and with Bak.
H. Mutational change to IAP that increases its affinity for caspases.
Answers: 3
Biology, 21.06.2019 20:30
Describe at least 2 abiotic and two biotic factors found in the desert biome how do these abiotic factors interact with the biotic factors
Answers: 1
Biology, 22.06.2019 02:20
Humans are believed to have evolved in coastal regions in east africa. the region had an abundant supply of fish for early humanoids to eat. when scientists analyze the fads gene they see an interesting pattern. people whose families have lived in this area of east africa for generation show a high level of diversity in alleles for the fads gene. conversely, people whose families had migrated inland a moderate distance from sources of fish showed a much lower diversity for fads gene alleles. additionally, the fads alleles found in people whose family has lived inland for generation are almost all gene alleles which produce fads proteins with a high level of function and activity. how do anthropologists explain this?
Answers: 3
Several mutational changes to proteins involved in apoptosis are listed below. For each, indicate wh...
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