Which component is releases from the active site of an enzyme during a chemical reaction

I’m doing some practice exam questions for biology, and i’m not sure how to do these 3 parts to the question.

Many organizations release indexes used to measure the development of the world's countries. as we learned in this lesson, these indexes measure many factors, from life expectancy to happiness. in your opinion, what are the three most important factors we can use to determine how developed a country might be? explain your answers in a few sentences.

Why did the federal government end its support of yucca mountain as a site for long-term storage of nuclear water