Describe ONE likely mechanism of action of a caspase inhibitor. Explain why an inhibitor for caspase 3 would likely be ineffective on caspase 9. (2 points)
Identify the dependent variable in the experiment whose data are graphed in Figure 2.
Identify the control group in the experiment. Justify the choice to monitor the cornea tissue
for a period of 12 days when it was exposed to caspase inhibitors. (3 points)
Based on the data in Figure 2, identify which caspase inhibitor was more effective at
preserving cornea tissue. Explain the most likely reason for the difference in effectiveness of
both caspase 3 and caspase 9 inhibitors. Calculate the rate of cell density degradation in the
control cornea tissue exposed to caspase 9 between days 4 and 6. (4 points)
Cytochrome C is a highly water-soluble component of the electron transport chain in cellular
respiration. Because of its polar nature, cytochrome C exits through pores in the
mitochondrial outer membrane. Based on Figure 1, predict the effect that a mutation causing
no pores to form in the mitochondrial outer membrane would have on the rate of apoptosis in
distressed cells. Provide evidence to support your prediction. (2 points)