From looking at the pedigree, how do you know if someone is a carrier?

where in your body is there an enzyme that does function at a high or low ph? what is the name of that enzyme and its function?

for example, no new evidence will demonstrate that the earth does not orbit around the sun (heliocentric theory), or that living things are not made of cells (cell theory), that matter is not composed of atoms, or that the surface of the earth is not divided into solid plates that have moved over geological timescales .