A cellular biologist is curious as to why a protein is not being expressed even though they placed the needed transcription factors and ribosomes allowing for the transcription and translation of the protein to take place in the cell. They look at the mRNA and find it is being translated and exported to the nucleus but ribosomes are not binding to it. After careful observation she finds out that the mRNA is missing its . Without this of course ribosomes would have an issue binding to the mRNA and inducing translation.