The current understanding of created "kinds" is:

The current understanding of created "kinds" is related to higher taxonomic orders and it is not easy to explain or define the created “kinds” like species. Taxonomy is the branch of science in which we study about the classification of something but mostly it is related to the classification of organisms.

they dont have any evidence

some inherited genetic mutations can be good for the offspring, so the answer is different genetic mutations cause many forms of cancer.