When did most marine life go extinct?

During the industrial revolution, it was easier for people dispose of there garbage. And more cars meant more pollution oil, and garbage have been leading factors to as why marine life is going extinct.  

While the other answers provides a viable answer, another possibility is during/right before any of the ice ages, as the freezing of water decreases the amount of livable space, and even changes the contours of the oceans (like the central american landbridge dividing the atlantic and pacific oceans), many species died out quickly (like the megalodon carcharodon).

Mitochondria is the cell organelle that produced the energy that is needed in the body system in form of atp, that is why it is called the power house of the cell. energy is needed by the living organisms to carry out the activities which sustain life.  if the mitochondria is destroyed atp will not be produced. if the mitochondria is destroyed, energy production will stop and the affected living organism will not have the energy to carry out the necessary life processes; this will lead to the death of the organism.

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