Which set of details correctly identifies a series of events in a sympathetic pathway?

thoracolumbar origin, long preganglionic fiber, ne release at ganglion, short postganglionic fiber, ne release at effector
craniosacral origin, short preganglionic fiber, ach release at ganglion, long postganglionic fiber, ach release at effector
thoracolumbar origin, short preganglionic fiber, ach release at ganglion, long postganglionic fiber, ne release at effector
craniosacral origin, long preganglionic fiber, ach release at ganglion, short postganglionic fiber, ach release at effector

Answer;

-Thoracolumbar origin, short preganglionic fiber, ACh release at ganglion, long postganglionic fiber, NE release at effector.

Explanation;

-The sympathetic nervous system is part of the autonomic nervous system, which also includes the parasympathetic nervous system. The sympathetic nervous system activates what is often termed the fight or flight response. The sympathetic nervous system operates through a series of interconnected neurons.

-In the sympathetic system, postganglionic are not all the same. Most sympathetic postganglionic neurons are adrenergic, but a few are cholinergic, such as the ones to sweat glands and to smooth muscles of certain blood vessels.

-In the cholinergic synapse, released acetylcholine is degraded down by the enzyme acetylcholinesterase, or reabsorbed into the preganglionic neuron. In the adrenergic synapse, released norepinephrine is either reabsorbed into the preganglionic neuron or degraded by catechol-o-methyl transferase enzyme.