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A mutation is a change that occurs in sequence of the DNA.

Explanation:

Mutation is capable of manipulating the genetic information carried by the genes. A mutagen is any agent which brings about changes in the genetic make up of an organism. Those mutations which occur at the somatic cells are called somatic mutations but those that occur at the germline cells are called as genetic mutations. The genetic mutations are heritable that means they are passed on from parents to their progenies.    

The genetic mutations are important as they bring about evolution of new traits in the generation of a particular species or in the generation of a particular individual. For example, genetic disorders and diseases caused by the genetic mutations are passed on to the next generation like cystic fibrosis, phenylketonuria, color blindness, and others. Thus identification of a particular genetic mutation is important to determine the cause of genetic diseases and disorders.