There are now several effective antimalarial drugs that can treat people who have malaria or prevent them from getting the disease altogether. Predict what will happen to the frequency of the sickle cell allele over the next 100 years as these drugs become more widely used by people living in areas where malaria is endemic: Predict what will happen to the frequency of the sickle cell allele over the next 100 years in areas like Boston MA, where there is no incidence of malaria: stay the same ; stay the same decrease ; increase increase ; increase increase ; decrease decrease ; decrease