When maintaining homeostasis in mammals antidiuretic hormone ( ADH ) is essential . In response to elevated tissue osmolarity ADH is released from the hypothalamus . The collecting duct and distal tubule in the kidney become more permeable to water in response to ADH , which increases water reabsorption into the capillaries . A negative feedback loop regulates the quantity of hormones released Which of the following statements reflects the proper relationship between osmolarity release of ADH and production of urine depending on the model presented ?