How enzymes inhibitions studies in the formulation and development of drugs​

Enzyme inhibitors may alter the elimination rate of a particular drug or inhibit detoxication pathways

Explanation:

An enzyme inhibitor is a chemical compound capable of binding to an enzyme in order to reduce its activity. An enzyme inhibitor may bind to an active site and thus decreases the rate of reaction (direct inhibition). Enzyme inhibitors may act 1-to Inhibit detoxification enzymes and 2-reduce the elimination rate of enzyme drugs, thereby having dose-dependent toxicity effects. For example, many medicines are based on the inhibition of Cytochromes P450 (CYPs) proteins, which are a superfamily of enzymes required for drug metabolism.

and after water is usually warmed by the sun the water temperature raises and then evaporates .

1. what is the relationship between the shape of an enzyme and the reactions they catalyze?

2. how does an enzyme inhibitor work?

separate your answers so i dont get confused : )