Collagen diseases are a group of human diseases in which the production of collagen throughout the body becomes impaired. Some examples of collagen diseases include systemic lupus erythematosus (SLE or lupus), rickets, and osteogenesis imperfecta. Explain why these diseases often affect the entire body. Hint: Consider the distribution of connective tissue throughout the body.

Explanation:

Collagen vascular disease is group of disease that affects the connective tissue.

Collagen is a protein based connective tissue that includes collagen and Elastin.

Collagen is found in the tendons, ligaments, skin, cornea, cartilage, bone and blood vessels while Elastin is a stretchy and formed the major component of ligaments and skin. This connective tissue holds, protect and connect and bind various body structures together both bones, ligaments, and muscles together. When a patient then has a connective tissue disease, the collagen is affected, the elastin are inflamed and every structure connected to the proteins in the body parts are harmed.

i think the answer would be d