What are the 4 pieces of evidence of Evolution?

fossils, anatomy, molecular biology, direct observation, biogeography

Explanation: i think theres 5 . hope this helpss

an active site is a region that is present on an enzyme where the reactants or the substrate molecules we can say bind and experience a chemical reaction. the substrate is basically a reactant whose concentration is changing and that is converting into a product after binding at the active site of an enzyme