Anhidrosis is the inability to sweat normally. If the human body cannot sweat properly, it cannot cool itself, which is potentially harmful. Anhidrosis most directly interferes with

Feedback mechanism that maintain homeostasis

Explanation:

This is because homeostasis is the ability to maintain internal environment and therefore a person with anhidrosis cannot sweat and it's body cannot cool because homeostasis is not maintained. It has effect on the negative feedback mechanism that maintain homeostasis because negative feedback can increase or decrease response to stimulus and inhibiting the stimulus ability to continue. This decrease the ability of the body to response to stimulus of heat which make to body to bring about cooking.

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explanation:

segmentation=endoskeleton=backbone=coelom=tissues