Enzymes can accelerate reactions by:. A) binding a substrate or substrates.
B) promoting the removal or addition of protons.
C) correctly positioning a metal ion for catalysis.
D) lowering the energy for activation.
E) all of the above.

D) lowering the energy for activation.

Explanation:

Just like chemical catalysts that accelerate the rate of chemical reactions, enzymes are biological catalysts that accelerate the rate of biochemical reactions.

Majorly, a catalyst works by lowering the activation energy required for a specific reaction. The lower the activation energy for a reaction, the faster the rate of that particular reaction.

Hence, an enzyme accelerates the rate of reaction by lowering activation energy of the reaction.