True or False:

The first step in glycogen synthesis is the phosphorylation of glucose.

The correct answer is True

Explanation:

The first step in glycogen synthesis (glycogenesis) is the phosphorylation of glucose to form glucose-6-phosphate, which is catalyzed by hexokinase. [This step is also the first step in the glycolytic pathway]. Glucose-6-phosphate is then isomerized to glucose-1-phosphate by the action of phosphoglucomutase. This glucose-i-phosphate is then converted to glycogen by glycogen synthase.