Which of the following is the most likely outcome of Leigh syndrome on affected mitochondria?

Which sentence best expresses the differing opinions of these two book reviews?

20. in humans, freckles are dominant to no freckles. trey has no freckles and his wife anna grace has freckles, but her dad doesn't. they want to know what percentage of their kids would look like trey. show a punnett square to support your answer.

The kidney filters potentially toxic substances in the blood, and thus “clears” the blood of those substances. this clearance function is dependent upon and proportional to the diffusion gradient of the substance across filtering capillaries, i.e. if the concentration of the substance is doubled, twice as much will be cleared from each ml of blood that is filtered. suppose that the body produces a constant amount of a substance x per unit of time. the kidneys eliminate substance x at a rate directly proportional to the concentration of the substance and the volume of blood cleared each minute (c): elimination = c × [x], where [x] is the steady-state concentration of substance x. imagine an individual with an initial concentration of x equal to [x]0 who develops kidney disease. her baseline clearance c0 drops to one half of the original (½c0). what is the new steady state concentration of x? (for simplicity, assume that substance x is 100% filtered by the kidney).