A channel protein specific for calcium ions was found to have a pore lined with six glutamate residues that participate in coordinating the calcium ion. What would happen to the selectivity of the pore if the Glu residues were mutated to Asp residues

If the mutation takes place, then the shorter side chains of asp compare to Glu  will affect the permeability of the transport protein to calcium ions. Specifically,  the mutation will  increase the sizes of the pore,which in turn decreases the selectivity  for calcium ion. Hence this affect excitability of the cell.

Explanation:

tsd is temerature dependent sex determination.

tsd: it is a type of environmental sex determination in which the temperature experienced during embryonic/ larval development (ambient temperature for development) determine the sex of the offspring.

crocodile displays the tsd where the ambient temperature of the developing egg determines the individual's sex. for example in the american alligator's eggs, incubation at 33 ºc produces mostly males, while incubation at 30 ºc produces mostly females. so if the american alligator's egg will get the ambient temperature (33 degree celcius)during embryonic development from egg, the offspring will be male and same for the female sex determination.

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