tay-sachs disease is an inborn errors of metabolism that results in death, often by the age of 2. You are a genetics counselor interviewing a phenotypically normal couple who tell you the male had a female first cousin(on the father's side) who died of TSD and the female had a maternal uncle with TSD. There are no other known cases in either of the families, and none of the mating have been between related individuals. Assume that the trait is very rare. Draw a pedigree of the families of those couple, showing relevant individuals. Calculate the probability that both the male and female are carries of TSD.
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tay-sachs disease is an inborn errors of metabolism that results in death, often by the age of 2. Yo...
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